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Studying Single mRNA Molecules from Cradle to GraveWe seek to understand the expression and movement of mRNA from transcription through degradation and the effect that defects in these processes have on health. RNA Localization: Following Single mRNAs from Birth to Death in Living Cells, Click this link to view the Singer Lab Publications.
Dr. Singer is professor and co-chair of anatomy & structural biology, the Harold and Muriel Block Chair in Anatomy & Structural Biology, and co-director of the Gruss-Lipper Biophotonics Center.
Eliscovich, C., Singer, R. H. & Yoon, Y. J. Because these techniques yield quantitative fluorescence data, we are able to apply mathematical modeling to test mechanistic hypotheses. Robert Einstein was born in 1884 in Munich, the son of Jakob Abraham Einstein. © 2020 Albert Einstein College of Medicine |, Master of Science in Clinical Research Methods (M.S. 1300 Morris Park Avenue Bronx, NY 10461 Fingerprint Dive into the research topics where Robert H. Singer is active. Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains. © 2020 Albert Einstein College of Medicine What Does it Look Like to 'Turn On' a Gene? Because these techniques yield quantitative fluorescence data, we are able to apply mathematical modeling to test mechanistic hypotheses. Together they form a unique fingerprint. Dr. Singer is professor ).
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Sato H, Wu B, Delahaye F, Singer RH, Greally JM. Tools For Imaging the Functional Genome in Living Cells and Tissues, Preventing neurodegeneration by boosting molecular chaperone expression, Mechanism of mRNA Localization and Localized Translation in Neurons, MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing, New generations of MS2 variants and MCP fusions to detect single mRNAs in living eukaryotic cells, Chapter in Book/Report/Conference proceeding, Simultaneous detection of mRNA and protein in S. cerevisiae by single-molecule FISH and immunofluorescence, Single-molecule imaging of transcription dynamics in somatic stem cells, Single molecule mRNA fluorescent in situ hybridization combined with immunofluorescence in S. cerevisiae: Dataset and quantification, http://www.einstein.yu.edu/faculty/7137/robert-singer/.
Science interviews Robert Singer, Ph.D., who is identified as a pioneer in the field of mRNA research, about the ongoing search to discover how proteins are placed in their correct destinations within a cell. He did postdoctoral work in molecular biology at the Massachusetts Institute of Technology …
Using these technologies, we can observe single mRNAs localizing to cytoplasmic compartments such as the leading edge of a fibroblast, the bud tip of yeast or the axonal process of neurons and follow these single mRNAs from transcription, nuclear export through translation and degradation. robert.singer@einstein.yu.edu Golding Room 601BA, +1.718.430.8646, faculty profile Studying Single mRNA Molecules from Cradle to Grave We seek to understand the expression and movement of mRNA from transcription through degradation and the effect that defects in these processes have on health.
Using these technologies, we can observe single mRNAs localizing to cytoplasmic compartments such as the leading edge of a fibroblast, the bud tip of yeast or the axonal process of neurons and follow these single mRNAs from transcription, nuclear export through translation and degradation.
These topic labels come from the works of this person.
Robert H Singer, PhD Harold and Muriel Block Chair Professor & Co-Chair of Anatomy & Structural Biology Professor of Cell Biology Professor of Neuroscience Co-Director, Gruss Lipper Biophotonics Center Co-Director, Integrated
The research of Robert Singer, Ph.D., and colleagues has illuminated our understanding of gene activation, or transcription.
Robert was a cousin of Nobel Prize Laureate Albert Einstein, as Hermann Einstein, Albert's father, was an older brother and business partner of Jakob Einstein, who persuaded his older …
We develop methods to label RNA in fixed and living cells using fluorescent probes and develop microscopy techniques and image analysis algorithms to visualize and quantify many mRNAs simultaneously. Recent external collaboration on country level.
Edit profile. Laboratory of Robert H. Singer, Ph.D. Publications 318. Dive into the research topics where Robert H. Singer is active. By continuing you agree to the use of cookies. Dr. Robert H. Singer received an undergraduate degree in physical chemistry from Oberlin College, and a PhD in developmental biology from Brandeis University. 21 Similar Profiles
If you made any changes in Pure these will be visible here soon. National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, Research output: Contribution to journal › Article, Research output: Chapter in Book/Report/Conference proceeding › Chapter, Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2020 Elsevier B.V, "We use cookies to help provide and enhance our service and tailor content.
718.430.2000, Department of Anatomy & Structural Biology, Dominick P. Purpura Department of Neuroscience, A Novel Approach to Identifying Partners of RNA-binding Proteins, Random Gene Expression is Critical for Stem Cell Function, In Scientific First, Researchers Visualize Proteins Being Born, Einstein and Berkeley Receive $4.25 Million from NIH for Next-Generation Gene Imaging, Master of Science in Clinical Research Methods (M.S. ). We develop methods to label RNA in fixed and living cells using fluorescent probes and develop microscopy techniques and image analysis algorithms to visualize and quantify many mRNAs simultaneously. We seek to understand the expression and movement of mRNA from transcription through degradation and the effect that defects in these processes have on health. Professor, Department of Anatomy & Structural Biology, Professor, Dominick P. Purpura Department of Neuroscience, Co-Chair Department of Anatomy & Structural Biology, Harold and Muriel Block Chair in Anatomy & Structural Biology, Co-Director, Gruss-Lipper Biophotonics Center, Albert Einstein College of MedicineJack and Pearl Resnick Campus1300 Morris Park AvenueGolding Building, Room 601Bronx, NY 10461, More Resources: Singer Laboratory Web PageASB Department Web Page, Is this your profile?
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